'Grey's Anatomy' - Katherine Heigl as Izzie Stevens

Is she headed down a dangerous road by sleeping with Alex? Katherine Heigl stars as Isobel "Izzie" Stevens in season five of ABC's hit medical drama Grey's Anatomy.

More About Grey's Anatomy

• Synopsis and Other Essential Information
• Spoilers/Episode Guide

Cast Biographies

• Ellen Pompeo
• Patrick Dempsey
• Katherine Heigl
• T.R. Knight
• Sandra Oh