'Grey's Anatomy' - Patrick Dempsey as Derek Shepard

Will Derek and Meredith live happily ever after? Patrick Dempsey stars as Derek Shepard in season five of ABC's hit medical drama Grey's Anatomy.

More About Grey's Anatomy

• Synopsis and Other Essential Information
• Spoilers/Episode Guide

Cast Biographies

• Ellen Pompeo
• Patrick Dempsey
• Katherine Heigl
• T.R. Knight
• Sandra Oh